Type 1 Diabetes TrialNet
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Information for Researchers

Living Biobank

In its mission to prevent type 1 diabetes, TrialNet has developed a unique resource through the longitudinal monitoring of individuals at risk for the development of type 1 diabetes within the Natural History study. TrialNet has launched the Living Biobank initiative to provide investigators with the opportunity to obtain "on-demand" biological samples from selected individuals within this population. Exploratory research is encouraged under this initiative.

Studies must use TrialNet screened subjects, and cannot interfere with ongoing clinical trials or studies. Investigators can select the clinical characteristics needed for their study as well as the sample type and collection frequency. Although many Living Biobank studies may be implemented through cost-sharing with the TrialNet network, special sample collections and visits outside of the normal visit schedules will incur additional costs which should be covered by the approved applicant. In addition, some studies may require effort from the TrialNet coordinating center, with costs covered by the approved ancillary study. See below for estimates of these costs (Living Biobank Cost List).

Living biobank studies must be reviewed and approved by TrialNet prior to initiation. Each proposal will be evaluated with careful consideration for its potential impact on the objectives and performance of the TrialNet Natural History study. Further, living biobank studies must not interfere with the continued interest and participation of the study subjects and investigators. All approved studies will be reviewed yearly to evaluate their progress and impact on TrialNet as a whole.

TrialNet welcomes the submission of living biobank studies as an adjunct to ongoing protocols. Please refer to the Living Biobank Applicant Instructions below for complete information.

Current Funding Opportunities

NIH general announcement for all investigator-initiated research: